Endocrine Abstracts

Background: Measuring testicular volumes by orchidometer is a standard method of pubertal staging in boys. A paucity of evidence exists as to its inter and intra-observer reliability and the impact of clinicians gender, experience and training on the accuracy of measurements. We are developing specifically engineered models with different testicular volumes to investigate inter and intra-observer reliability of testicular volume estimation for simulation training.<p class=...

AimWe appreciate the effect of testosterone undecanoat 1000 mg intramuscular injection (NebidoR; Bayer) on both prostatic volume (see Peretianu, this congress) and PSA (this study) in hypogonadic patients after up to 13 years.Material and methodA. PSA (ng/ml) was done in Bucharest accredited laboratories, appreciated at 1 year. B. Prostatic volume (PV): ultrasound,...

Introduction: There is no concensus whether euthyroid children with Hashimoto’s thyroiditis (HT) need treatment with thyroxine.Aim of the study: To assess whether thyroxine influences goitre progression (calculated thyroid volume on U/S scan) in euthyroid children with HT.Subjects and methods: We studied 50 euthyroid children with HT for a 2-year period. Children with a multinodular goitre were not included in the study. Twent...

Introduction and aim: Mean platelet volume (MPV) is a new important indicator of platelet activity in atherosclerosis. Elevated MPV is associated with the presence of more metabolically active platelets. The aim of our study is to evaluate whether change of MPV value is associated with cabergoline treatment in patients with prolactinoma.Materials and methods: Thirty patients with prolactinoma (mean age 33.4±8.5 years and body mass index (BMI): 28.1&...

Introduction and aim: The incidence of atherosclerotic vascular disease is high in obesity. Our aim is to determine the mean platelet volume (MPV) as a new indicator of atherosclerosis in morbid obesity.Materials and methods: Thirty-three patients with morbid obesity who applied to endocrinology department (mean age 41.5±11.3 years, body weight 118.2±16.9 kg and BMI: 45.9±7.2 kg/m2) and 39 age-matched (mean age 35.3±13.1 ye...

Aim: Mean platelet volume (MPV) is considered a new indicator of atherosclerosis. Activated platelets and subclinical inflammation predispose to create for atherosclerotic heart disease. Larger platelets are metabolically more active than smaller ones and have more protrombotic potential. We have recently demonstrated that MPV levels in Hashimoto’s patients tend to be higher than healthy controls even if in euthyroid state. In present study we aimed to investigate a relat...

Introduction and objective: Platelets play an important role in the development of thrombotic events. Increase of mean platelet volume (MPV) may indicate pre-thrombotic conditions as a new cardiovascular marker. Larger platelets have been reported to be metabolically more active than smaller ones. Our aim of present study is to evaluate MPV levels in patients with papillary thyroid cancer.Materials and methods: Forty-seven patients with newly diagnosis m...

Measuring of goiter by ultrasonography is one of the generally accepted methods for iodine nutrition assessment. Discordance between previously used and lately proposed thyroid volume (TV) reference values (TVRV) is the subject of discussion and makes it difficult to properly interpret the effects of iodine prophylaxis.Aim: To establish TVRV for Polish schoolchildren population.Material and methods: 2903 schoolchildren aged 6–...

Background: There is much debate about the best imaging modality for parathyroid adenoma. Parathyroid ultrasound is operator dependent and in skilled hands leads to localisation of tumour. Small adenomas can be difficult to detect and radiologists are helped by clinical and biochemical data to predict ease of adenoma detection. We investigated whether any factors could predict adenoma size.Methodology: This was a retrospective CWS analysis of patients wh...

Aim: Hashimoto’s thyroiditis (HT) is an autoimmune disease in which a breakdown of immune tolerance is caused by interplay of a variety of immunologic, genetic, and environmental factors. Mean platelet volume (MPV) is the measure of platelet size. MPV possibly is a simple way to estimate platelet activity. Activated platelets play an important role in the pathogenesis of vascular disease especially coronary heart diseases. Larger platelets are metabolically and enzymatica...